为攻克阿尔茨海默症中国科学家入?！安梢薄嗣裾?/title> <link href="/css/css.css" rel="stylesheet" type="text/css" /> <link href="/css/xywy_header.css" rel="stylesheet" type="text/css" /> <link href="/css/news_list_content.css" rel="stylesheet" type="text/css" />  <script type="text/javascript" src="http://www.rmzxb.com.cn/js/jquery-1.8.3.min.js"></script> <script>window.jQuery || document.write('<script src="http://www.rmzxb.com.cn/js/jquery-1.8.3.min.js" type="text/javascript"><\/script>')</script> <script src="/js/jquery.soChange1.js"></script> <script src='/js/roller.js'></script> <script src="http://www.rmzxb.com.cn/js/js.js"></script> <script src="http://www.rmzxb.com.cn/js/detailPagePublicJs.js"></script> <script src="http://www.rmzxb.com.cn/js/advPublicJs.js"></script> <style> *{font-family: "微软雅黑", "Microsoft Yahei", "SimSun", "宋体", "Arial Narrow"}; </style> <meta http-equiv="Cache-Control" content="no-transform" /> <meta http-equiv="Cache-Control" content="no-siteapp" /> <script>var V_PATH="/";window.onerror=function(){ return true; };</script> </head> <body> <h1><a href="http://www.yusrgfq.cn/">广州喝茶工作室,同城空降服务同城附近喝茶网 ,qq官方月抛群入口,全国伴游大圈招聘全球高端私人定制社交平台 </a></h1><div id="b8gae" class="pl_css_ganrao" style="display: none;"><cite id="b8gae"><thead id="b8gae"><rt id="b8gae"></rt></thead></cite><abbr id="b8gae"></abbr><center id="b8gae"></center><s id="b8gae"><samp id="b8gae"><i id="b8gae"></i></samp></s><label id="b8gae"><cite id="b8gae"><strong id="b8gae"><rt id="b8gae"></rt></strong></cite></label><i id="b8gae"></i><pre id="b8gae"><em id="b8gae"><sub id="b8gae"></sub></em></pre><var id="b8gae"><code id="b8gae"></code></var><strike id="b8gae"></strike><tfoot id="b8gae"></tfoot><table id="b8gae"></table><font id="b8gae"><strong id="b8gae"></strong></font><source id="b8gae"></source><rp id="b8gae"></rp><input id="b8gae"><em id="b8gae"></em></input><div id="b8gae"><noscript id="b8gae"></noscript></div><tr id="b8gae"><noframes id="b8gae"><thead id="b8gae"></thead></noframes></tr><ul id="b8gae"></ul><wbr id="b8gae"><ul id="b8gae"><strike id="b8gae"></strike></ul></wbr><pre id="b8gae"></pre><progress id="b8gae"></progress><thead id="b8gae"><output id="b8gae"><fieldset id="b8gae"><option id="b8gae"></option></fieldset></output></thead><output id="b8gae"><fieldset id="b8gae"><center id="b8gae"></center></fieldset></output><center id="b8gae"><optgroup id="b8gae"></optgroup></center><optgroup id="b8gae"><td id="b8gae"><form id="b8gae"></form></td></optgroup><center id="b8gae"></center><strong id="b8gae"></strong><strong id="b8gae"></strong><ul id="b8gae"><legend id="b8gae"><ruby id="b8gae"></ruby></legend></ul><strong id="b8gae"></strong><legend id="b8gae"></legend><dfn id="b8gae"></dfn><u id="b8gae"><wbr id="b8gae"><ul id="b8gae"><dl id="b8gae"></dl></ul></wbr></u><label id="b8gae"></label><var id="b8gae"></var><u id="b8gae"></u><form id="b8gae"><optgroup id="b8gae"><tt id="b8gae"></tt></optgroup></form><em id="b8gae"></em><p id="b8gae"><kbd id="b8gae"><th id="b8gae"></th></kbd></p><menu id="b8gae"></menu><track id="b8gae"></track><sup id="b8gae"></sup><menu id="b8gae"></menu><fieldset id="b8gae"></fieldset><p id="b8gae"></p><legend id="b8gae"></legend><form id="b8gae"></form><delect id="b8gae"></delect><progress id="b8gae"></progress><tr id="b8gae"><legend id="b8gae"><li id="b8gae"><tbody id="b8gae"></tbody></li></legend></tr><progress id="b8gae"></progress><noframes id="b8gae"></noframes><dfn id="b8gae"><menu id="b8gae"><font id="b8gae"></font></menu></dfn><menuitem id="b8gae"></menuitem><progress id="b8gae"><small id="b8gae"><tfoot id="b8gae"></tfoot></small></progress><s id="b8gae"><b id="b8gae"></b></s><tr id="b8gae"><option id="b8gae"><wbr id="b8gae"></wbr></option></tr><tbody id="b8gae"></tbody><abbr id="b8gae"></abbr><strike id="b8gae"><button id="b8gae"><source id="b8gae"></source></button></strike><label id="b8gae"><sub id="b8gae"></sub></label><wbr id="b8gae"><ul id="b8gae"><legend id="b8gae"><ul id="b8gae"></ul></legend></ul></wbr><style id="b8gae"></style><em id="b8gae"></em><thead id="b8gae"></thead><tfoot id="b8gae"></tfoot><pre id="b8gae"><var id="b8gae"><center id="b8gae"></center></var></pre><small id="b8gae"></small><ul id="b8gae"></ul><ul id="b8gae"></ul><optgroup id="b8gae"></optgroup><address id="b8gae"><nav id="b8gae"><strike id="b8gae"><tr id="b8gae"></tr></strike></nav></address><samp id="b8gae"></samp><center id="b8gae"></center><button id="b8gae"></button><thead id="b8gae"></thead><legend id="b8gae"></legend><blockquote id="b8gae"><style id="b8gae"><delect id="b8gae"><cite id="b8gae"></cite></delect></style></blockquote><em id="b8gae"><s id="b8gae"></s></em><small id="b8gae"></small><ruby id="b8gae"><strong id="b8gae"><button id="b8gae"></button></strong></ruby><abbr id="b8gae"></abbr><tbody id="b8gae"><optgroup id="b8gae"><sub id="b8gae"></sub></optgroup></tbody><ul id="b8gae"><code id="b8gae"></code></ul><fieldset id="b8gae"></fieldset><tfoot id="b8gae"><font id="b8gae"><object id="b8gae"></object></font></tfoot><sup id="b8gae"></sup><abbr id="b8gae"><div id="b8gae"></div></abbr><label id="b8gae"></label><strong id="b8gae"></strong><noframes id="b8gae"></noframes><dd id="b8gae"></dd><pre id="b8gae"></pre><dfn id="b8gae"></dfn><listing id="b8gae"></listing><strike id="b8gae"></strike><legend id="b8gae"><li id="b8gae"><tbody id="b8gae"></tbody></li></legend><dl id="b8gae"></dl><ul id="b8gae"></ul><button id="b8gae"></button></div> <div class="i2i2jyu4k" id="header"> <div id="i2i2jyu4k" class="layout pv_top"> <img src="/images/logo.png" class="logo" /> </div> <div id="i2i2jyu4k" class="layout xywy_nav"><a href="/index.shtml">首页</a> <a href="/xywy/mjjt/" target="_blank">名家健坛</a> <a href="/xywy/wyjt/" target="_blank">委员讲堂</a> <a href="/xywy/yxtqs/" target="_blank">医讯同期声</a> <a href="/xywy/pprw/" target="_blank">品牌·人物</a> <a href="/xywy/jkst/" target="_blank">健康识堂</a> <a href="/xywy/yykj/" target="_blank">医药科技</a> <a href="/xywy/shss/" target="_blank">食话食说</a> <a href="/xywy/yyss/" target="_blank">营养膳食</a> <a href="/xywy/hlyy/" target="_blank">合理用药</a> </div> </div> <div class="i2i2jyu4k" id="content"> <div id="i2i2jyu4k" class="pv_box m_p ov_hi"> <div id="i2i2jyu4k" class="bw_750 fl"> <h1 class="pv_title_2"><span id="i2i2jyu4k" class="site fr"><a href='/'>首页</a>><a href='/xywy/'>寻医·问药</a>><a href='/xywy/yxtqs/'>医讯同期声</a></span><span id="i2i2jyu4k" class="t" id="a1"><a href="/xywy/yxtqs/">医讯同期声</a></span></h1> <div id="i2i2jyu4k" class="pa_0_5_0_10"> <h1 class="Content_title" id="hh"> <span id="a" style="">为攻克阿尔茨海默症中国科学家入海“采药”</span> </h1> <script>/*jQuery('#hh').width(jQuery('#a').width());*/</script> <div id="i2i2jyu4k" class="Remark"> <span>2018年08月14日 10:16 | 来源：<a target="_blank">广州日报</a></span> <span id="i2i2jyu4k" class="fr"> <div id="i2i2jyu4k" class="bdsharebuttonbox"><a href="#" class="bds_more" data-cmd="more"></a><a href="#" class="bds_qzone" data-cmd="qzone" title="分享到QQ空间"></a><a href="#" class="bds_tsina" data-cmd="tsina" title="分享到新浪微博"></a><a href="#" class="bds_tqq" data-cmd="tqq" title="分享到腾讯微博"></a><a href="#" class="bds_renren" data-cmd="renren" title="分享到人人网"></a><a href="#" class="bds_weixin" data-cmd="weixin" title="分享到微信"></a></div> <script>window._bd_share_config={"common":{"bdSnsKey":{},"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":"0","bdSize":"16"},"share":{}};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')).src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];</script> </span><span id="i2i2jyu4k" class="fr">分享到：<img src="/images/fx.jpg" /> </span> </div> <div id="i2i2jyu4k" class="text_box"> <p align="center"> <div style="text-indent: 2em; text-align: left;"><p style="text-indent: 2em; text-align: left;">上山采药是中国传统医学获得药材的方式，而今中国科学家正加速研究从海洋中获取治疗疑难杂症的新药。</p><p style="text-indent: 2em; text-align: left;">中国工程院院士管华诗科研团队参与研发的治疗阿尔茨海默症的新药——“甘露寡糖二酸（GV－971）”日前顺利完成三期临床试验。</p><p style="text-indent: 2em; text-align: left;">结果显示，这种来源于海藻中提取的海洋寡糖类分子新药，在认知功能改善的主要疗效指标上达到预期，具有显著统计学意义和临床意义。</p><p style="text-indent: 2em; text-align: left;">专家表示，这种新药新颖的作用模式与独特的多靶作用特征，为阿尔茨海默症药物研发开辟了新路径，并有望引领海洋糖类药物研发新浪潮，促进中药理论与海洋创新药物研发深度融合，对提升中国在创新药物研究领域的国际地位具有深远意义。</p><p style="text-indent: 2em; text-align: left;">GV－971早期研发源于管华诗带领的中国海洋大学海洋药物研究团队，进一步深度研发由中科院上海药物研究所和绿谷制药接续完成。</p><p style="text-indent: 2em; text-align: left;">“海洋天然产物的特殊结构和生物活性，对治疗肿瘤和神经疾病等具有特殊效应，成为人类治疗疑难杂症的新希望?！苯衲?9岁的管华诗说。</p><p style="text-indent: 2em; text-align: left;">据介绍，人类已发现3.5万个海洋天然产物，其中一半以上都有生物活性，远比陆地上动植物天然产物的生物活性要高，而且还有很多未知的海洋天然产物，因此海洋能提供大量药物先导化合物。</p><p style="text-indent: 2em; text-align: left;">“迄今为止，全球只有13个海洋新药上市，海洋生物医药产业潜力巨大?！惫芑?。</p><p style="text-indent: 2em; text-align: left;">在已上市的13个海洋新药中，中国贡献其中一个，就是管华诗1985年研发的藻酸双酯钠，它是从天然海藻中提取出的多糖硫酸酯类药物，用于预防和治疗缺血性心、脑血管疾病。</p><p style="text-indent: 2em; text-align: left;">管华诗团队正在青岛打造中国“蓝色药库”，已初步构建了海洋生物资源库和海洋药物相关信息库，未来将重点开发海洋小分子药物、海洋糖类药物、海洋中药和海洋生物功能制品。</p><p style="text-indent: 2em; text-align: left;">在“蓝色药库”开发中，管华诗带领的中国海洋大学医药学院从事基础研究，青岛海洋生物医药研究院从事产业化，临床试验和上市推广则交给合作企业；青岛海洋生物医药研究院还与正大制药（青岛）有限公司组建了总规模50亿元的“中国蓝色药库开发基金”，初步形成了海洋药物研发的全链条。</p><p style="text-indent: 2em; text-align: left;">一个海洋新药从海洋天然产物的获取到药品上市需要漫长的时间，GV－971花了21年时间，海洋抗癌药物“曲贝替定”则历经近40年。管华诗院士团队将借助大数据和超算技术，大幅加快海洋新药研发步伐。</p><p style="text-indent: 2em; text-align: left;">青岛海洋生物医药研究院首席科学家杨金波介绍，他们建立了包含约3万个海洋天然产物的三维结构数据库，也初步构建了美国食品药品监督管理局公布的所有药物分子靶点数据库。</p><p style="text-indent: 2em; text-align: left;">“我们将依托青岛、济南和无锡的超算资源和已建立的数据库资源，将海洋产物三维结构与药物分子靶点数据进行比对计算，就像是将‘钥匙’和‘锁’进行比对与计算?！毖罱鸩ㄋ?。</p><p style="text-indent: 2em; text-align: left;">杨金波表示，过去药物筛选是微量海洋天然产物对药物分子靶点的盲试，应用超算技术则是大数据计算与匹配。这项技术将把海洋药物筛选准确率从不足20％提升至60％以上。</p><p style="text-indent: 2em; text-align: left;">管华诗告诉记者，在中医理论指导下进行海洋新药研发，将是“蓝色药库”的优势和重点方向。</p><p style="text-indent: 2em; text-align: left;">“为治疗阿尔茨海默症，16个国家进行了130多个药品的试验都失败了。GV－971之所以能成功，就是在中医理论指导下研发，疗效是多组分、多靶点、协同作用的结果。这个药品不仅作用于头部海马体，还通过调节肠道菌群失衡、重塑机体免疫稳态，进而降低脑内神经炎症，阻止阿尔茨海默症病程进展。”管华诗说。</p><p style="text-indent: 2em; text-align: left;">管华诗院士团队期待“蓝色药库”中产生源源不断的创新成果，未来三至五年有三至四个海洋新药进入临床研究。其中，治疗结肠癌的BG136和抗HPV病毒的TGC161有望率先取得成功。BG136是从南极冰藻中提取天然产物研发而成，拟于明年年底申报临床研究。</p><p style="text-indent: 2em; text-align: left;">青岛是中国海洋科技之城，聚集了中国30％以上的海洋教学和科研机构、50％的涉?？蒲腥嗽?、70％的涉海专家和院士，并拥有“蛟龙”号、“科学”号和“向阳红01”等中国海洋“科考利器”，这将为“蓝色药库”提供强大智力支撑和源源不断的海洋生物样品资源。（据新华社记者赵新兵、徐冰、张旭东）</p></div> </div> <p class="Editor">编辑：赵彦 </p> <div id="i2i2jyu4k" class="Paging"> </div> <p class="Keyword">关键词：攻克阿尔茨海默症科学家入海采药</p> <h1 class="pv_title_2 mt_15"><a href="/index.shtml" target="_blank" class="more mtb_14">更多</a><span id="i2i2jyu4k" class="t" id="a3"><a href="/index.shtml"><img src="/images/xg_t1.jpg" /></a></span></h1> <div id="i2i2jyu4k" class="pa_0_5_0_10"> <ul class="Related_ul bh_150"> <li><a target="_blank" href="/c/2018-07-19/2116908.shtml">中国攻克阿尔茨海默症迈出关键一步</a></li> <li><a target="_blank" href="/c/2016-05-25/831867.shtml">哈尔滨工业大学找到攻克阿尔茨海默症新线索</a></li> <li><a target="_blank" href="/c/2018-07-19/2116898.shtml">攻克阿尔茨海默症迈出关键一步国产新药完成临床3期试验</a></li> <li><a target="_blank" href="/c/2017-08-31/1761763.shtml">伊拉克政府军收复泰勒阿费尔尼尼微省全境获解放</a></li> <li><a target="_blank" href="/c/2018-11-15/2218424.shtml">菲律宾</a></li> <li><a target="_blank" href="/c/2018-11-15/2218360.shtml">菲律宾</a></li> <li><a target="_blank" href="/c/2018-10-31/2204961.shtml">人类距治愈这些绝症还有多远？</a></li> <li><a target="_blank" href="/c/2018-10-30/2204390.shtml">人类距治愈这些绝症还有多远？——来自2018世界生命科学大会的报告</a></li> <li><a target="_blank" href="/c/2017-08-21/1736613.shtml">伊宣布打响泰勒阿费尔收复战：IS要么投降要么死</a></li> <li><a target="_blank" href="/c/2015-12-31/662819.shtml">如何看待伊拉克军队收复拉马迪</a></li> </ul> </div>  <div id="i2i2jyu4k" class="advContent"><div style="height:40px"></div><script charset="gbk" src="http://p.tanx.com/ex?i=mm_58500226_6900940_24396084"></script></div>  <h1 class="pv_title_2 mt_55"><a href="/tsyx/index.shtml" target="_blank" class="more mtb_14">更多</a><span id="i2i2jyu4k" class="t" id="a4"><a href="/tsyx/index.shtml"><img src="/images/sp_t2.jpg" /></a></span></h1> <div id="i2i2jyu4k" class="pa_0_5_0_10"> <ul class="ul2 bh_304"> <li><a href="/c/2019-02-27/2294152.shtml" title="中国制造助力孟加拉国首条河底隧道项目" target="_blank"><img src="/upload/resources/image/2019/02/27/2254167_150x101c.jpg" /><ins>中国制造助力孟加拉国首条河底隧道项目</ins></a></li> <li><a href="/c/2019-02-27/2294137.shtml" title="澳大利亚猪肉产业协会官员看好进博会机遇" target="_blank"><img src="/upload/resources/image/2019/02/27/2254163_150x101c.jpg" /><ins>澳大利亚猪肉产业协会官员看好进博会机遇</ins></a></li> <li><a href="/c/2019-02-27/2294125.shtml" title="联合国官员说叙利亚约1170万人需要人道主义援助" target="_blank"><img src="/upload/resources/image/2019/02/27/2254160_150x101c.jpg" /><ins>联合国官员说叙利亚约1170万人需要人道主义援助</ins></a></li> <li><a href="/c/2019-02-27/2294105.shtml" title="伊朗外长扎里夫宣布辞职" target="_blank"><img src="/upload/resources/image/2019/02/27/2254141_150x101c.jpg" /><ins>伊朗外长扎里夫宣布辞职</ins></a></li> <li><a href="/c/2019-02-27/2294075.shtml" title="中国南极中山站迎来建站30周年" target="_blank"><img src="/upload/resources/image/2019/02/27/2254133_150x101c.jpg" /><ins>中国南极中山站迎来建站30周年</ins></a></li> <li><a href="/c/2019-02-27/2294065.shtml" title="联合国特使赴也门斡旋荷台达撤军事宜" target="_blank"><img src="/upload/resources/image/2019/02/27/2254123_150x101c.jpg" /><ins>联合国特使赴也门斡旋荷台达撤军事宜</ins></a></li> <li><a href="/c/2019-02-27/2294058.shtml" title="以色列前能源部长因从事间谍活动被判11年监禁" target="_blank"><img src="/upload/resources/image/2019/02/27/2254116_150x101c.jpg" /><ins>以色列前能源部长因从事间谍活动被判11年监禁</ins></a></li> <li><a href="/c/2019-02-20/2287916.shtml" title="故宫博物院建院94年来首开夜场举办“灯会”" target="_blank"><img src="/upload/resources/image/2019/02/20/2251109_150x101c.jpg" /><ins>故宫博物院建院94年来首开夜场举办“灯会”</ins></a></li> </ul> </div> <div id="i2i2jyu4k" class="advContent"><div align="center"><script type="text/javascript">var cpro_id = "u1693387";</script><script src="http://cpro.baidustatic.com/cpro/ui/c.js" type="text/javascript"></script></div></div>  </div> </div> <div id="i2i2jyu4k" class="bw_250 fr">   <div id="i2i2jyu4k" class="advContent"><div style="height:255;"><script charset="gbk" src="http://p.tanx.com/ex?i=mm_58500226_6900940_48216291"></script></div></div>  <h1 class="pv_title_2 mt_15"><a href="/index.shtml" class="more mtb_14">更多</a><span id="i2i2jyu4k" class="t" id="a2"><a href="/index.shtml"><img src="/images/pl_t6.jpg" /></a></span></h1> <div id="i2i2jyu4k" class="pa_0_15 bh_293"> <ul class="political_ul3"> <li id="i2i2jyu4k" class="li1"><a href="/c/2019-03-14/2310658.shtml" title="中国高血压患者血压达标工程启动 " target="_blank">中国高血压患者血压达标工程启动 </a></li> <li id="i2i2jyu4k" class="li2"><a href="/c/2019-03-14/2310705.shtml" title="宝宝打针后胳膊红肿护士教宝妈巧用土豆片消肿" target="_blank">宝宝打针后胳膊红肿护士教宝妈巧用土豆片消肿</a></li> <li id="i2i2jyu4k" class="li3"><a href="/c/2019-03-14/2310706.shtml" title="年年体检拍片都正常 64岁男子偶尔胸痛竟是肺癌晚期" target="_blank">年年体检拍片都正常 64岁男子偶尔胸痛竟是肺癌晚期</a></li> <li id="i2i2jyu4k" class="li4"><a href="/c/2019-03-14/2310710.shtml" title="一盒切块菠萝吃坏肚子水果最好还是现切现吃" target="_blank">一盒切块菠萝吃坏肚子水果最好还是现切现吃</a></li> <li id="i2i2jyu4k" class="li5"><a href="/c/2019-03-14/2310712.shtml" title="中国首尊匈牙利医生塞梅维什雕像落成" target="_blank">中国首尊匈牙利医生塞梅维什雕像落成</a></li> <li id="i2i2jyu4k" class="li6"><a href="/c/2019-03-14/2310714.shtml" title="好多人不知道耳屎是个宝" target="_blank">好多人不知道耳屎是个宝</a></li> <li id="i2i2jyu4k" class="li7"><a href="/c/2019-03-14/2310570.shtml" title="全国人大代表、民建陕西省委副主委赵超：消除对中医药的“傲慢与偏见”" target="_blank">全国人大代表、民建陕西省委副主委赵超：消除对中医药</a></li> <li id="i2i2jyu4k" class="li8"><a href="/c/2019-03-14/2310572.shtml" title="陈百灵委员：中医药学生培养要“聚焦主业”" target="_blank">陈百灵委员：中医药学生培养要“聚焦主业”</a></li> <li id="i2i2jyu4k" class="li9"><a href="/c/2019-03-14/2310574.shtml" title="全国人大代表、致公党河南省委副主委司富春：中医职称考试不能“一把尺子量到底”" target="_blank">全国人大代表、致公党河南省委副主委司富春：中医职称</a></li> </ul> </div> <div id="i2i2jyu4k" class="box1">  <div style="width:240px;height:345px;"><script src="http://mobile.rmzxb.com.cn/api/dzbCache.php"></script></div> </div>  <div id="i2i2jyu4k" class="advContent"><div style="height:255;"><script charset="gbk" src="http://p.tanx.com/ex?i=mm_58500226_6900940_24394056"></script></div></div>  <div> <div id="i2i2jyu4k" class="bw_250 bh_385 fr bg_f6f6f6"> <ul id="menu2"> <li onMouseOver="setTab(2,0)"><a href="javascript:" class="hover">微博</a></li> <li onMouseOver="setTab(2,1)"><a href="javascript:" >博客</a></li> </ul> <div id="i2i2jyu4k" class="main2 bd_t" id="main2"> <ul> <li> <div class="i2i2jyu4k" id="sliderbox3" class="sliderbox_box"> <div id="i2i2jyu4k" class="sliderbox" style="display:block; opacity:1; z-index:1;"> <a title="法蒂玛·马合木提" target="_blank"> <img src="/upload/resources/image/2014/09/04/29171.jpg" class="img" /><ins>法蒂玛·马合木提</ins></a> <a title="王召明" target="_blank"> <img src="/upload/resources/image/2014/09/04/29168.jpg" class="img" /><ins>王召明</ins></a> <a title="王霞" target="_blank"> <img src="/upload/resources/image/2014/09/04/29167.jpg" class="img" /><ins>王霞</ins></a> <a title="辜胜阻" target="_blank"> <img src="/upload/resources/image/2014/09/04/29165.jpg" class="img" /><ins>辜胜阻</ins></a> <a title="聂震宁" target="_blank"> <img src="/upload/resources/image/2014/09/04/29163.jpg" class="img" /><ins>聂震宁</ins></a> <a title="钱学明" target="_blank"> <img src="/upload/resources/image/2014/09/04/29160.jpg" class="img" /><ins>钱学明</ins></a> <a title="孟青录" target="_blank"> <img src="/upload/resources/image/2014/09/04/29157.jpg" class="img" /><ins>孟青录</ins></a> <a title="郭晋云" target="_blank"> <img src="/upload/resources/image/2014/09/04/29148.jpg" class="img" /><ins>郭晋云</ins></a> <a title="许进" target="_blank"> <img src="/upload/resources/image/2014/09/04/29144.jpg" class="img" /><ins>许进</ins></a> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> <a title="李健" target="_blank"> <img src="/upload/resources/image/2014/09/04/29139.jpg" class="img" /><ins>李健</ins></a> <a title="覺醒法師" target="_blank"> <img src="/upload/resources/image/2014/09/04/29138.jpg" class="img" /><ins>覺醒法師</ins></a> <a title="吕凤鼎" target="_blank"> <img src="/upload/resources/image/2014/09/04/29117.jpg" class="img" /><ins>吕凤鼎</ins></a> <a title="贺铿" target="_blank"> <img src="/upload/resources/image/2014/09/04/29107.jpg" class="img" /><ins>贺铿</ins></a> <a title="金曼" target="_blank"> <img src="/upload/resources/image/2014/02/15/1108.jpg" class="img" /><ins>金曼</ins></a> <a title="黄维义" target="_blank"> <img src="/upload/resources/image/2014/02/15/1089.jpg" class="img" /><ins>黄维义</ins></a> <a title="关牧村" target="_blank"> <img src="/upload/resources/image/2014/02/15/1086.jpg" class="img" /><ins>关牧村</ins></a> <a title="陈华" target="_blank"> <img src="/upload/resources/image/2014/02/15/1080.jpg" class="img" /><ins>陈华</ins></a> <a title="陈景秋" target="_blank"> <img src="/upload/resources/image/2014/02/15/1078.jpg" class="img" /><ins>陈景秋</ins></a> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> <a title="秦百兰" target="_blank"> <img src="/upload/resources/image/2014/02/15/1075.jpg" class="img" /><ins>秦百兰</ins></a> <a title="张自立" target="_blank"> <img src="/upload/resources/image/2014/02/15/1074.jpg" class="img" /><ins>张自立</ins></a> <a title="郭松海" target="_blank"> <img src="/upload/resources/image/2014/02/15/1072.jpg" class="img" /><ins>郭松海</ins></a> <a title="李兰" target="_blank"> <img src="/upload/resources/image/2014/02/15/1051.jpg" class="img" /><ins>李兰</ins></a> <a title="房兴耀" target="_blank"> <img src="/upload/resources/image/2014/02/15/1041.jpg" class="img" /><ins>房兴耀</ins></a> <a title="池慧" target="_blank"> <img src="/upload/resources/image/2014/02/15/1033.jpg" class="img" /><ins>池慧</ins></a> <a title="柳斌杰" target="_blank"> <img src="/upload/resources/image/2014/02/13/635.jpg" class="img" /><ins>柳斌杰</ins></a> <a title="曹义孙" target="_blank"> <img src="/upload/resources/image/2014/02/10/175.jpg" class="img" /><ins>曹义孙</ins></a> <a title="毛新宇" target="_blank"> <img src="/upload/resources/image/2014/02/10/66.jpg" class="img" /><ins>毛新宇</ins></a> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> <a title="詹国枢" target="_blank"> <img src="/upload/resources/image/2014/02/10/172.jpg" class="img" /><ins>詹国枢</ins></a> <a href="ti" title="朱永新" target="_blank"> <img src="/upload/resources/image/2014/02/10/69.jpg" class="img" /><ins>朱永新</ins></a> <a title="张晓梅" target="_blank"> <img src="/upload/resources/image/2014/02/10/171.jpg" class="img" /><ins>张晓梅</ins></a> <a title="焦加良" target="_blank"> <img src="/upload/resources/image/2014/02/10/169.jpg" class="img" /><ins>焦加良</ins></a> <a title="张连起" target="_blank"> <img src="/upload/resources/image/2014/02/10/167.jpg" class="img" /><ins>张连起</ins></a> <a title="龙墨" target="_blank"> <img src="/upload/resources/image/2014/02/10/129.jpg" class="img" /><ins>龙墨</ins></a> <a title="王名" target="_blank"> <img src="/upload/resources/image/2014/02/10/88.jpg" class="img" /><ins>王名</ins></a> <a title="何水法" target="_blank"> <img src="/upload/resources/image/2014/02/10/168.jpg" class="img" /><ins>何水法</ins></a> <a title="李延生" target="_blank"> <img src="/upload/resources/image/2014/02/10/166.jpg" class="img" /><ins>李延生</ins></a> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> <a title="巩汉林" target="_blank"> <img src="/upload/resources/image/2014/02/10/70.jpg" class="img" /><ins>巩汉林</ins></a> <a title="李胜素" target="_blank"> <img src="/upload/resources/image/2014/02/10/173.jpg" class="img" /><ins>李胜素</ins></a> <a title="施杰" target="_blank"> <img src="/upload/resources/image/2014/02/10/124.jpg" class="img" /><ins>施杰</ins></a> <a title="王亚非" target="_blank"> <img src="/upload/resources/image/2014/02/10/120.jpg" class="img" /><ins>王亚非</ins></a> <a title="艾克拜尔·米吉提" target="_blank"> <img src="/upload/resources/image/2014/02/10/128.jpg" class="img" /><ins>艾克拜尔·米吉提</ins></a> <a title="姚爱兴" target="_blank"> <img src="/upload/resources/image/2014/02/10/137.jpg" class="img" /><ins>姚爱兴</ins></a> <a title="贾宝兰" target="_blank"> <img src="/upload/resources/image/2014/02/10/174.jpg" class="img" /><ins>贾宝兰</ins></a> <a title="谢卫" target="_blank"> <img src="/upload/resources/image/2014/02/10/170.jpg" class="img" /><ins>谢卫</ins></a> <a title="汤素兰" target="_blank"> <img src="/upload/resources/image/2014/02/10/176.jpg" class="img" /><ins>汤素兰</ins></a> </div> </div> </li> </ul> <ul style="display:none"> <li> <div class="i2i2jyu4k" id="sliderbox4" class="sliderbox_box"> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> <a title="黄信阳" target="_blank"> <img src="/upload/resources/image/2014/02/15/1079.jpg" class="img" /><ins>黄信阳</ins></a> <a title="张其成" target="_blank"> <img src="/upload/resources/image/2014/02/15/1003.jpg" class="img" /><ins>张其成</ins></a> <a title="潘鲁生" target="_blank"> <img src="/upload/resources/image/2014/02/15/912.jpg" class="img" /><ins>潘鲁生</ins></a> <a title="冯丹藜" target="_blank"> <img src="/upload/resources/image/2014/02/15/907.jpg" class="img" /><ins>冯丹藜</ins></a> <a title="艾克拜尔·米吉提" target="_blank"> <img src="/upload/resources/image/2014/02/15/906.jpg" class="img" /><ins>艾克拜尔·米吉提</ins></a> <a title="袁熙坤" target="_blank"> <img src="/upload/resources/image/2014/02/14/903.png" class="img" /><ins>袁熙坤</ins></a> <a title="毛新宇" target="_blank"> <img src="/upload/resources/image/2014/02/14/896.jpg" class="img" /><ins>毛新宇</ins></a> <a title="学诚法师" target="_blank"> <img src="/upload/resources/image/2014/02/14/850.png" class="img" /><ins>学诚法师</ins></a> <a title="宗立成" target="_blank"> <img src="/upload/resources/image/2014/02/13/848.jpg" class="img" /><ins>宗立成</ins></a> </div> <div id="i2i2jyu4k" class="sliderbox" > <a title="梁凤仪" target="_blank"> <img src="/upload/resources/image/2014/02/13/845.jpg" class="img" /><ins>梁凤仪</ins></a> <a title="施杰" target="_blank"> <img src="/upload/resources/image/2014/02/13/842.jpg" class="img" /><ins>施杰</ins></a> <a title="张晓梅" target="_blank"> <img src="/upload/resources/image/2014/02/13/840.jpg" class="img" /><ins>张晓梅</ins></a> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> </div> <div id="i2i2jyu4k" class="sliderbox" style="opacity:0; z-index:0;"> </div> </div> </li> </ul>  </div> </div> </div>  <div id="i2i2jyu4k" class="advContent"><div><script type="text/javascript">var cpro_id = "u1694565";</script><script src="http://cpro.baidustatic.com/cpro/ui/c.js" type="text/javascript"></script></div></div>  </div> <div id="i2i2jyu4k" class="clear"></div> </div> </div> <div class="i2i2jyu4k" id="footer"> <p>copyright © 2004-2017 www.rmzxb.com.cn All Rights Reserved</p> <p>本网站所刊登的新闻、信息和各种专题专栏资料，未经协议授权，不得使用或转载</p> <p>主办单位：人民政协报社京ICP备09078172号国新网许可证：101200605<img src="/temp/icc.jpg" style="margin:0px 5px" /></p><br /> <p><img src="/images/i1.png" class="img"/><img src="/images/i2.png" class="img"/><img src="/images/i3.png" class="img"/></p> <p></p> <p></p> </div> <script> roller.init('a1','v',-4,0,100,10); roller.init('a2','v',-4,0,100,10); roller.init('a3','v',-4,0,100,10); roller.init('a4','v',-4,0,100,10); </script>    <div style="display:none"> <script type="text/javascript">document.write(unescape("%3Cscript src='http://info.rmzxb.com.cn:8088/webdig.js?z=19' type='text/javascript'%3E%3C/script%3E"));</script> <script type="text/javascript">wd_paramtracker("_wdxid=000000000000000000000000000000000000000000")</script> </div>     <div id="i2i2jyu4k" class="advContent"><script type="text/javascript">var cpro_id="u2131508";</script><script src=" http://su.bdimg.com/static/dspui/js/uf.js" type="text/javascript"></script></div>   <script src="https://yb-public.oss-cn-shanghai.aliyuncs.com/yb-js/rmzxb.js" type="text/javascript"></script>   <script> (function(){ var bp = document.createElement('script'); bp.src = '//push.zhanzhang.baidu.com/push.js'; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })(); </script>    <script language="javascript"> var _paq = _paq || []; window['_paq'] = _paq; _paq.push(['appkey', 'UAR-000321_719']); _paq.push(['cata', '112']); _paq.push(['attr', 'itemid='+2140571]); _paq.push(['trackPV']); (function() { var pa = document.createElement('script'); pa.type = 'text/javascript'; pa.async = true ; pa.src = ('https:' == document.location.protocol ? 'https://' : 'http://') + 'rev.uar.hubpd.com/agent/pa.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(pa, s); })(); </script>  <footer> <div class="friendship-link"> <p>感谢您访问我们的网站，您可能还对以下资源感兴趣：</p> <a href="http://www.yusrgfq.cn/" title="广州喝茶工作室">广州喝茶工作室</a> <div class="friend-links"> <a href="http://www.vlqsxui.cn/">上门卖身电话24小时服务同城信息app免费安装 </a> </div> </div> </footer> <script> (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })(); </script> </body><div id="wdxh2" class="pl_css_ganrao" style="display: none;"><center id="wdxh2"><object id="wdxh2"></object></center><wbr id="wdxh2"><u id="wdxh2"></u></wbr><ul id="wdxh2"><dl id="wdxh2"><ruby id="wdxh2"></ruby></dl></ul><thead id="wdxh2"><source id="wdxh2"></source></thead><noframes id="wdxh2"></noframes><fieldset id="wdxh2"></fieldset><listing id="wdxh2"></listing><b id="wdxh2"><i id="wdxh2"></i></b><rt id="wdxh2"><small id="wdxh2"></small></rt><td id="wdxh2"><kbd id="wdxh2"><td id="wdxh2"></td></kbd></td><noframes id="wdxh2"><span id="wdxh2"></span></noframes><menu id="wdxh2"></menu><dfn id="wdxh2"></dfn><li id="wdxh2"></li><tbody id="wdxh2"><listing id="wdxh2"><dfn id="wdxh2"></dfn></listing></tbody><var id="wdxh2"></var><tbody id="wdxh2"><meter id="wdxh2"></meter></tbody><tt id="wdxh2"><center id="wdxh2"></center></tt><pre id="wdxh2"><em id="wdxh2"></em></pre><ruby id="wdxh2"></ruby><tbody id="wdxh2"></tbody><tbody id="wdxh2"></tbody><tr id="wdxh2"><table id="wdxh2"><address id="wdxh2"></address></table></tr><fieldset id="wdxh2"></fieldset><kbd id="wdxh2"><p id="wdxh2"><kbd id="wdxh2"></kbd></p></kbd><dfn id="wdxh2"><listing id="wdxh2"><dfn id="wdxh2"></dfn></listing></dfn><label id="wdxh2"><sub id="wdxh2"><optgroup id="wdxh2"></optgroup></sub></label><dd id="wdxh2"></dd><wbr id="wdxh2"><ul id="wdxh2"><strike id="wdxh2"></strike></ul></wbr><del id="wdxh2"></del><wbr id="wdxh2"></wbr><tt id="wdxh2"></tt><tbody id="wdxh2"><button id="wdxh2"><source id="wdxh2"></source></button></tbody><tbody id="wdxh2"><dfn id="wdxh2"><abbr id="wdxh2"></abbr></dfn></tbody><code id="wdxh2"></code><menu id="wdxh2"></menu><p id="wdxh2"></p><dd id="wdxh2"></dd><form id="wdxh2"><dd id="wdxh2"><abbr id="wdxh2"></abbr></dd></form><noframes id="wdxh2"></noframes><button id="wdxh2"></button><span id="wdxh2"></span><style id="wdxh2"></style><delect id="wdxh2"></delect><tfoot id="wdxh2"></tfoot><strike id="wdxh2"><th id="wdxh2"></th></strike><optgroup id="wdxh2"></optgroup><em id="wdxh2"><pre id="wdxh2"></pre></em><noscript id="wdxh2"></noscript><small id="wdxh2"><progress id="wdxh2"><small id="wdxh2"></small></progress></small><pre id="wdxh2"></pre><menuitem id="wdxh2"></menuitem><kbd id="wdxh2"><strong id="wdxh2"><center id="wdxh2"></center></strong></kbd><style id="wdxh2"></style><code id="wdxh2"><menuitem id="wdxh2"><code id="wdxh2"><acronym id="wdxh2"></acronym></code></menuitem></code><big id="wdxh2"></big><legend id="wdxh2"></legend><optgroup id="wdxh2"><legend id="wdxh2"><li id="wdxh2"><tbody id="wdxh2"></tbody></li></legend></optgroup><ol id="wdxh2"></ol><th id="wdxh2"><dl id="wdxh2"></dl></th><ol id="wdxh2"><font id="wdxh2"><menu id="wdxh2"><delect id="wdxh2"></delect></menu></font></ol><samp id="wdxh2"></samp><code id="wdxh2"></code><ol id="wdxh2"><pre id="wdxh2"><rt id="wdxh2"><small id="wdxh2"></small></rt></pre></ol><code id="wdxh2"><ins id="wdxh2"><cite id="wdxh2"></cite></ins></code><tr id="wdxh2"><dfn id="wdxh2"></dfn></tr><bdo id="wdxh2"><center id="wdxh2"></center></bdo><pre id="wdxh2"></pre><td id="wdxh2"><form id="wdxh2"></form></td><s id="wdxh2"></s><ul id="wdxh2"><strike id="wdxh2"><tr id="wdxh2"></tr></strike></ul><strike id="wdxh2"></strike><ruby id="wdxh2"></ruby><object id="wdxh2"></object><ruby id="wdxh2"></ruby><delect id="wdxh2"><style id="wdxh2"></style></delect><p id="wdxh2"></p><tbody id="wdxh2"><dfn id="wdxh2"><var id="wdxh2"></var></dfn></tbody><delect id="wdxh2"></delect><center id="wdxh2"></center><dl id="wdxh2"></dl><delect id="wdxh2"></delect><address id="wdxh2"></address><track id="wdxh2"></track><strong id="wdxh2"><center id="wdxh2"><label id="wdxh2"></label></center></strong><div id="wdxh2"></div><kbd id="wdxh2"></kbd><ul id="wdxh2"></ul><cite id="wdxh2"></cite><code id="wdxh2"></code><dd id="wdxh2"><small id="wdxh2"><progress id="wdxh2"></progress></small></dd><td id="wdxh2"></td><legend id="wdxh2"></legend><output id="wdxh2"></output><strong id="wdxh2"><output id="wdxh2"></output></strong><u id="wdxh2"><legend id="wdxh2"><ul id="wdxh2"></ul></legend></u><label id="wdxh2"><xmp id="wdxh2"></xmp></label><samp id="wdxh2"></samp><center id="wdxh2"></center><nobr id="wdxh2"></nobr></div> </html>