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<script>window._bd_share_config={"common":{"bdSnsKey":{},"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":"0","bdSize":"16"},"share":{}};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')).src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];</script> </span><span id="i2i2jyu4k" class="fr">分享到：<img src="/images/fx.jpg" /> </span> </div> <div id="i2i2jyu4k" class="text_box"> <p align="center"> <p style="text-indent: 2em; text-align: left;">资料显示，止咳药水滥用在我国男性青少年群体中有明显的流行趋势。近期一项研究发现，止咳药水成瘾患者在脑功能和脑结构方面均存在异常。历经8年创新性研究，广东省第二人民医院和华南师范大学科研团队终于发现海洛因和止咳药水会“改变”人的大脑。</p><p style="text-indent: 2em; text-align: left;">据知，这些脑区功能与结构的异常与成瘾时间、冲动特质和临床表现有很大的相关性。异常主要集中在奖赏回路、认知控制和决策相关的脑区。</p><p style="text-indent: 2em; text-align: left;">项目第一完成人、广东省第二人民医院院长田军章介绍，国内的慢性药物成瘾研究相对较少，特别是对于合法非处方药物止咳药水的研究，社会学乃至医学上对其认识尚不足，成瘾的神经生理学机制也不完全清楚，因此临床上缺少有效诊断、疗效评估及预后判断的影像学指标，严重限制了止咳药水成瘾患者的积极治疗和康复。</p><p style="text-indent: 2em; text-align: left;">田军章带领团队，遴选了30名20岁—50岁的海洛因成瘾患者、80名20岁—50岁的慢性止咳药水成瘾患者进行组间研究，还选取30名经过美沙酮治疗的海洛因成瘾患者进行研究。结果发现，海洛因成瘾患者和止咳药水成瘾患者在脑功能和脑结构方面均存在异常，主要集中在奖赏回路、认知控制和决策相关的脑区，如眶额叶皮层、扣带皮层、丘脑、楔叶等区域。这为指导临床提供了重要的影像支持。对于慢性止咳药水成瘾患者，该研究还发现，患者的抑制控制相关前额叶皮层灰质体积减少，且该脑区的受损与患者极高的冲动性有关。</p><p style="text-indent: 2em; text-align: left;">项目第二完成人、广东省第二人民医院影像科主任江桂华介绍，但凡有药物成瘾者，因滥用药物、毒品导致大脑皮层变薄的患者，要比正常人群易冲动、嗜赌。在毒品、药物给患者带来幻想、幻觉的同时，他们可能会因为这一类冲动而导致轻生等可怕的后果。（记者李颖）</p> </div> <p class="Editor">编辑：赵彦 </p> <div id="i2i2jyu4k" class="Paging"> </div> <p class="Keyword">关键词：止咳药水滥用大脑结构异常</p> <h1 class="pv_title_2 mt_15"><a href="/index.shtml" target="_blank" class="more mtb_14">更多</a><span id="i2i2jyu4k" class="t" id="a3"><a href="/index.shtml"><img src="/images/xg_t1.jpg" /></a></span></h1> <div id="i2i2jyu4k" class="pa_0_5_0_10"> <ul class="Related_ul bh_150"> <li><a target="_blank" href="/c/2018-02-06/1955337.shtml">治咳为何不能随意用止咳药？</a></li> <li><a target="_blank" 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